The most common treatment (and maybe the most effective) these days is Ruxolitinib (Jakafi) which has great results shrinking the spleen. When used early, it also gives a modest benefit in terms of lifespan. A lecture by Dr. Verstovsek given just 3 weeks ago noted that shrinking the spleen early on delayed more serious complications like weight loss and that it's best used before a patient becomes too anemic. Those who don't benefit from Jakafi after 6 months may be switched to a newer kinase inhibitor fedratinib (Inrebic). Nice that there are choices these days. Best thing anyone with MPN can do is get with a MPN specialist. Good luck!

My spleen is also enlarged. I did look up "Foods Shrink Spleen" along with "Foods Raise Hemoglobin" but have been paying more attention to the hemoglobin so I can function better. Look it up. I'm sure you'll find some interesting things.

My spleen is enlarged as well. I have PMF and began Jakafi almost immediately along with a clinical trial drug. I hope this was helpful.

You may want to consult your doctor and have another bone marrow biopsy. I had ET for little less than 2 years. I became anemic, had night sweats and found my spleen was enlarged. I have since been rediagnosed with Myelofibrosis according to the BMB and my symptoms. Im on the list for a BM transplant with MD Anderson. I had no idea I had transitioned over. I knew it was a possibility but was under the impression this would happen in the later stage pf the disease not 2 years after diagnosis. Im currently taking Jakafi which seems to be helping some. Good luck to you.

Thanks will do!