It is a important to distinguish the different types of numbness-tingling that can occur in relation to MPNs and their treatment.

MPN related paresthesia is a known phenomenon. While not… read more

I have continuous ringinging in ear and my doc says it's nothing to do with MPN. But I think it is because of low blood flow in head and neck
What could be the possible reasons of this ringing in… read more

I and several other people on here have MDS and MPN and JAK2 mutation as well as other mutations. Leukemia is what we’ve been trying to avoid with treatment. Some have less or more of a propensity to… read more

Dear Renee,

The 2016 WHO classification and diagnostic criteria for myeloproliferative neoplasms always includes a bone marrow biopsy to distinguish between ET/PV and PMF
https://www.ncbi.nlm.nih.g… read more

I have MF with negative Jak2. I take Jakafi. Goal is to decrease my spleen size. I will not know if working till after six months. I'm about to enter my 5th month this month (Aug)

Hi Edna,

Tinnitus in ET and PV is considered to be due to too many blood cells (platelets in ET and red blood cells in PV) in the blood vessels
"ET may also cause hearing problems, such as tinnitus… read more

The official information is that there is no cure. I could read about the odd case that went into remission, but that seems to be more the exception than the rule. Several of those cases needed bone… read more

Here's another source to consider. It's a 2017 scholarly article that discusses familial cases of MPNs (genetic predisposition. The authors say this: “In our experience, about 7% to 8% of patients… read more

I receive disability for multiple conditions

I've got big time ringing too, but some of it is from all the loud music over the years. Having ET has definitely made it worse. Over the years I have gotten used to it and I'm able to put it out of… read more