Thanks for your perspective, Barbara. (I think brain fog might be my new normal-haha!) But seriously, my MD believes my iron levels are currently ok, but suggested I take a women’s regular daily multivitamin to boost my B12 & D intake. He will include a review of a handful of vitamin levels plus FE at my next blood analysis to confirm any deficiencies.

I had a small increase and my Doctor said that's how they know I am taking the Hydroxy. So there must be an affect. Going for blood work every three months.

I have PV and my Red Cell Distribution Width (RDW) has been high for several years. I do not take HU, yet, just phlebotomy. However, when I had iron studies and a bone marrow done summer 2020, they found my iron and Ferritin low and iron stores in BM depleted. I have been on iron since then and RDW is coming down. I have read that low iron can cause brain fog, too. Hope this info helps.

I'd ask your doc. My RDW has been high ranging from 16%--24.6% My JAK2 V617F were confirmed from blood draw on 7/11/2019; and because of other lab results from that draw was then put on HU and Aspirin. So my RDW was high prior to ever going on HU.

My hematology oncologist is aware and watchful. Told me that’s why I have monthly bloodwork and he sees me every 3 months.