I know many people are taking this combo. Is anyone on this forum? If so, how are you doing on it? What dose of IFN & RUX are you taking? How long have you been doing it? What is your diagnosis? I'm ET JAK2+ & will be discussing this combo with my MPN specialist at my next appointment but wanted to get input from those that are currently on it. TYIA!
I tried Angrelide for one month and it caused me to have high blood pressure (mine was always 100/68), dizziness and headaches. I was taken off immediately and put back on Hydrea! My next visit we will discuss which med to place me in as Hydrea causes severe diarrhea if take every other day. I’m taking it only every third night.
IFN lowered my PLT immediately. It is the only Rx out there that has documented cases of halting the progression of our condition or causung molecular remission. It is usually recommended for younger patients because of this & also for women who may want to get pregnant since you can't be on HU while pregnant. If I could tolerate IFN, I'd still be on it as I've seen several people post on blogs I follow that have gone in remission &/or have not progressed while being on it & have been able to get off it all together after a couple years (or significantly lower their dose).
I am on Pegysas and Anagralide. My platelets came down then have continued to go up the last few weeks. So not sure what the next course of action is
I had so many issues with Hydrea. Nausea, vomiting, neck pain from being sick so much, headaches, nerve issues so I needed anti nauseas meds, nerve pain meds, and a few others. I cannot remember the names, but I ended up being on 8 different meds as a result :( They wanted me to start Anagrelide, but I just started having high bp, so they have me on medication for it. If it increases, it then they will put me on something else. I read about Interferon, have you tried that?
I was on Hydrea for almost 2 years and have major memory loss from it. My hair is naturally fine and it was coming out, a lot. I could not remember things then and still have issues remembering things now. I used to have an amazing memory.
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