Connect with others who understand.

  • Learn from expert-reviewed resources
  • Real advice from people who’ve been there
  • People who understand what you’re going through
Sign Up Log In
Powered By
Real members of myMPNteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

https://www.pvreporter.com/mpns-and-alzheimers-...

July 1, 2023
 · 
Reactions
A myMPNteam Member

Interesting because im losing my memry is anybody else havin this problem.

July 2, 2023
A myMPNteam Member

Yes I have been suffering the same

July 2, 2023
A myMPNteam Member

Another very insightful post from you, Tatiana. You provide a lot of food for thought, and we certainly need plenty of that to try to stay on top of our many dilemmas.

October 4, 2023 (edited)
A myMPNteam Member

Dear MaryAnn,

Thank you for this link.

This discussion is even more important these days as it has become more and more obvious that Alzheimer's is a disease in which immunity has a significant involvement.
MPNs are also producing immune changes, via several mechanisms, from what I could read, so it is not unlikely that there could be an intersection between MPNs and Alzheimer's.
Over the last years there are quite some publications on MPNs and immunity.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10...
And some hypothesise Alzheimer's could be some sort of autoimmunity (https://pubmed.ncbi.nlm.nih.gov/36165334/), and we know that autoimmunity and MPNs are linked (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC28...).
As another hypothesis is that Alzheimer's could be due to previous infections (https://www.ox.ac.uk/news/2022-08-02-viral-role...), and as people with MPNs are more susceptible to infections (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC77...), that could also be a potential explanation.

Probably we are in a way lucky to live now, when there is enough knowledge, as this gives more hope for more targeted treatments for us in the not so far away future.

Many hugs of support,
Tatiana

October 4, 2023
A myMPNteam Member

My fathers side of the family has been riddled with Alzheimer’s! My father, his mom, all her siblings, and most of my dads first and second cousins all had it! One cousin had Lou Garrick dx and his daughter (my 2nd cousin- a Dr) said that LG dx and Alzheimer dx are related diseases

July 17, 2023

Related Questions

View All
Continue with Facebook
Continue with Google
By joining, you accept our Terms of Use, and acknowledge our collection, sharing, and use of your data in accordance with our Health Data and Privacy policies.
Already a member? Log In