Connect with others who understand.

  • Learn from expert-reviewed resources
  • Real advice from people who’ve been there
  • People who understand what you’re going through
Sign up Log in
What is This Site Help Center Crisis
Powered By
Real members of myMPNteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Does Anyone Here Know If JAK2 Inhibitor Meds Work If You Are JAK2 Negative? Just Curious...I'll Ask My Doc Next Visit As Well.

A myMPNteam Member asked a question 💭
Galway, IE
August 6, 2023
•
View reactions
A myMPNteam Member

Hi IrishHiker!

This study below gives a nice explanation regarding JAK inhibitors in myeloproliferative neoplasms 👇
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC36...
You do not need to have a JAK-positive MPN for JAK inhibitors to be useful.

Best regards,
Tatiana

August 6, 2023
A myMPNteam Member

I have MF with negative Jak2. I take Jakafi. Goal is to decrease my spleen size. I will not know if working till after six months. I'm about to enter my 5th month this month (Aug)

August 7, 2023
A myMPNteam Member

Thank you

August 6, 2023

Related content

View All

Anyone With Familial MPN? My 27 Y/o Was Just Diagnosed With ET Nearly One Year After Me, 52 Y/o.

A myMPNteam Member asked a question 💭
Irvine, CA
January 31, 2024

Does Everyone With The JAK2 Mutation Have Their Allele Burden Checked? If So, How Often?

A myMPNteam Member asked a question 💭
Illinois City, IL
May 19

For An Initial Treatment Start, Did Anyone Forgo Hydroxyurea For Another Treatment Just Because They Didn't Like The Side Effects Possible.

A myMPNteam Member asked a question 💭
Wilkes Barre, PA
December 29, 2024

What Is a JAK2 Mutation?
Does Night Shift Work Increase the Risk for Myeloproliferative Neoplasms?
Polycythemia Vera: Causes, Symptoms, and Treatments
Continue with Facebook
Continue with Google
By joining, you accept our Terms of Use, and acknowledge our collection, sharing, and use of your data in accordance with our Health Data and Privacy policies.
Already a Member? Log in