If You Have Taken Pegasys Or Besremi, Have They Affected Your Mood (irritability, Anxiety, Or Depression)? | myMPNteam

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If You Have Taken Pegasys Or Besremi, Have They Affected Your Mood (irritability, Anxiety, Or Depression)?
A myMPNteam Member asked a question 💭

I'm 58 with ET JAK2 and my platelet count is in the low to mid 600s. I'm considering starting Pegasys or Besremi (clinical trial) early rather than wait until I reach 60. I don't think I would mind physical side effects, but I would be less tolerant of mood changes. Have either Pegasys or Besremi affected your mood? Or did you have any other side effects that required you to stop taking them? Thanks for sharing.

posted December 2, 2023 (edited)
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A myMPNteam Member

Thanks for sharing your experience Janet. It helps a lot. I understand that I could also experience unacceptable physical side effects, but it's the potential mood changes that concern me most. I'm glad Bomedemstat has worked for you instead. Pegasys and Besremi are generally well tolerated, so I'm hopeful that if I decide to take one it will be favorable.

posted December 2, 2023
A myMPNteam Member

Curious to read the responses

posted December 13, 2023
A myMPNteam Member

I was on interferon, Pegasys, for a little over a year. No effects on my mood and that was surprising considering I experience anxiety, but unacceptable physical side effects. Everyone is different. Consider all the possible side effects.

posted December 2, 2023

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