I was taking Anegralide for 6 months- I had a heart attack purely because of the drug- I knew from the start it wasn’t right- I had all the bad signs on the instructions but at the time I only had a haematologist looking after me NOT an MPN specialist! I now have a superb MON specialist( this is so important)- he told me he never prescribes Anegralide as he is not comfortable with this drug.
I was on Hydroxyeurea for 24 years in variyi g strengths and a when it stopped working this is when I was out on Anegralide. I didn’t have many side effects in all of those years!
I am on Peg interferon now! Good luck!

I don’t know how much hydrea you are taking, but if it is multiple capsules daily try splitting them up between morning and evening. This worked for me. Also, have your water ready and get them down quickly. All the best.

I have been on 500 mgm of hydrea daily for almost three years and have mouth sores frequently. I take it with a meal and drink a lot of water which helps.

Hi Patty2,
I understand how you feel about not wanting to try Anagrelide because of the heart side effects. It is true that no medication is perfect, and each medication has its own risks. I think you are right in saying that you will seek a second opinion from a specialist who will have more insight and help you find the best treatment for you. Your doctor will help you find ways to reduce the effects of Hydroxyurea or try other medications.
Sometimes seeing a doctor can open up new avenues that you were not aware of, and I hope you find the right balance. Good luck and stay strong..💗

Hi JillLancaster,
Thank you so much for sharing your experience. I really appreciate the information you provide about using HU. Hearing that you have not had any side effects and that it has been helpful all along makes me feel more secure. I hope to find the right medication for me as you have shared. Thanks again