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These blood characteristics (high RBC, hemoglobin, and hematocrit with low EPO) are commonly associated with polycythemia vera (PV), though being JAK2 negative is less common. While approximately 95% of PV cases are JAK2 positive, there is a small percentage of cases that can be JAK2 negative. To confirm a diagnosis Show Full Answer

These blood characteristics (high RBC, hemoglobin, and hematocrit with low EPO) are commonly associated with polycythemia vera (PV), though being JAK2 negative is less common. While approximately 95% of PV cases are JAK2 positive, there is a small percentage of cases that can be JAK2 negative. To confirm a diagnosis, doctors typically perform several tests including:
• Complete blood count with differential
• Bone marrow biopsy
• Genetic testing using methods like quantitative polymerase chain reaction (qPCR) or fluorescent in situ hybridization (FISH)

It would be important to discuss these blood results with a hematologist who can perform additional testing to determine the underlying cause and appropriate treatment plan.

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

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