How are anemia and Hydrea (hydroxyurea) related?
Hydroxyurea is a common treatment for myeloproliferative neoplasms, but it can actually cause or worsen anemia. This happens because hydroxyurea suppresses bone marrow function, which can lead to lower red blood cell production.
If your anemia becomes severe enough, your Show Full Answer
How are anemia and Hydrea (hydroxyurea) related?
Hydroxyurea is a common treatment for myeloproliferative neoplasms, but it can actually cause or worsen anemia. This happens because hydroxyurea suppresses bone marrow function, which can lead to lower red blood cell production.
If your anemia becomes severe enough, your doctor may need to adjust your treatment plan. Hydroxyurea is not recommended for people with severe anemia because it can make the condition worse.
Some myMPNteam members have shared their experiences:
- One member reported that hydroxyurea "wreaked havoc" on their bloodwork and caused anemia severe enough to require two blood transfusions
- Another member mentioned their doctor stopped phlebotomies after becoming anemic while on treatment
If you're experiencing worsening anemia symptoms like increased fatigue, weakness, shortness of breath, or dizziness while taking hydroxyurea, it's important to discuss this with your healthcare team. They may need to adjust your dosage or explore alternative treatment options.
Never stop taking hydroxyurea without talking to your doctor first, as they need to carefully manage any medication changes.
December 10, 2025
Continue with Facebook
Continue with Email
Join
Your Privacy Choices
