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Real members of myMPNteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
March 2
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Are neuropathy side effects common with hydroxyurea in MPN patients?

Neuropathy isn't typically listed among the common side effects of hydroxyurea for MPN patients. The more frequently reported side effects include:

* Mouth ulcers (especially at higher doses)
* Chronic ankle ulcers (in about 5% of people)
* Low blood Show Full Answer

Are neuropathy side effects common with hydroxyurea in MPN patients?

Neuropathy isn't typically listed among the common side effects of hydroxyurea for MPN patients. The more frequently reported side effects include:

* Mouth ulcers (especially at higher doses)
* Chronic ankle ulcers (in about 5% of people)
* Low blood cell counts (anemia, low white blood cells, low platelets)
* Nosebleeds, bleeding gums, and easy bruising
* Diarrhea and constipation
* Darkened skin
* Nausea and upset stomach
* Increased risk of skin cancer

If you're experiencing symptoms that feel like neuropathy while taking hydroxyurea, it's important to discuss this with your healthcare provider. They can help determine whether your symptoms might be related to the medication, your MPN itself, or another cause.

Never stop taking your medication without talking to your doctor first, even if you're experiencing challenging side effects.

March 2

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