Drenching night sweats are very common with MPNs — and you are definitely not alone in dealing with them. Many myMPNteam members have shared experiences like waking up completely soaked through their nightwear and bedding, with one member even coining the term "SINS" — sleep-interrupting night sweats! Night sweats happen Show Full Answer
Drenching night sweats are very common with MPNs — and you are definitely not alone in dealing with them. Many myMPNteam members have shared experiences like waking up completely soaked through their nightwear and bedding, with one member even coining the term "SINS" — sleep-interrupting night sweats! Night sweats happen because MPNs cause the body to produce excess cytokines, proteins that trigger inflammation and sweating. They tend to be more common in people with myelofibrosis (MF) and polycythemia vera (PV) than in those with essential thrombocythemia (ET). There are several ways to help manage night sweats. Here are some practical tips:
- Keep your bedroom cool by turning down the thermostat
- Use lighter bedding and loose, breathable cotton nightwear
- Drink cool water before bed to help regulate body temperature
- Practice good sleep hygiene — consistent bedtime, no electronics before sleep, and relaxation techniques like meditation or breathing exercises
- Avoid alcohol, nicotine, caffeine, and late meals On the medical treatment side, ruxolitinib (Jakafi), a JAK2 inhibitor, has been shown to help reduce night sweats by blocking the cytokines that cause them. It's worth speaking with your doctor or a specialist about treatment options — they can also help determine whether your night sweats are MPN-related or have another contributing cause.
1 day ago
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