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List of Treatments for Myeloproliferative Neoplasms

See what members are saying about MPN treatments, the side effects to expect, and the drug basics.

All treatment information is medically reviewed · September 14, 2026

Besremi (Ropeginterferon Alfa-2b)

Overview
Besremi is approved by the U.S. Food and Drug Administration (FDA) specifically for the treatment of polycythemia vera (PV), a type of myeloproliferative neoplasm characterized by the overproduction of red blood…

Bosulif (Bosutinib)

Overview
Bosulif is approved by the U.S. Food and Drug Administration (FDA) for treating Philadelphia chromosome-positive chronic myelogenous leukemia (Ph+ CML), a type of myeloproliferative neoplasm (MPN), in adults and…

Gleevec (Imatinib Mesylate)

Overview
Gleevec is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat adults and children with Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) — a type of…

Iclusig (Ponatinib)

Overview
Iclusig is approved by the U.S. Food and Drug Administration (FDA) to treat certain types of chronic myeloid leukemia (CML), a type of myeloproliferative neoplasm (MPN), in adults. Doctors prescribe Iclusig to…

Imkeldi (Imatinib Mesylate)

Overview
Imkeldi is approved by the U.S. Food and Drug Administration (FDA) to treat certain types of myeloproliferative neoplasms (MPNs), including Philadelphia chromosome-positive (Ph-positive) chronic myeloid leukemia…

Inrebic (Fedratinib)

Overview
Inrebic is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat adults with intermediate or high-risk primary or secondary myelofibrosis, a cancer of the bone marrow. Inrebic is…

Jakafi/Jakafi XR (Ruxolitinib) for Myeloproliferative Neoplasms

Jakafi/Jakafi XR (ruxolitinib) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with intermediate- or high-risk myelofibrosis, a type of myeloproliferative neoplasm (MPN).

Mimrylo (Rusfertide)

Mimrylo (rusfertide) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat erythrocytosis (too many red blood cells) in adults with polycythemia vera (PV).

Ojjaara (Momelotinib)

Overview
Ojjaara is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat adults with myelofibrosis (MF) and anemia (low red blood cell count). Ojjaara may be recommended to treat…

Phyrago (Dasatinib)

Overview
Phyrago is approved by the U.S. Food and Drug Administration (FDA) to treat chronic myeloid leukemia (CML), a type of blood cancer that belongs to a group called myeloproliferative neoplasms (MPNs). Phyrago is…

Scemblix (Asciminib)

Overview
Scemblix is approved by the U.S. Food and Drug Administration (FDA) to treat adults with Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) in the chronic phase. This includes newly diagnosed…

Sprycel (Dasatinib)

Overview
Sprycel is a prescription drug approved by the U.S. Food and Drug Administration (FDA) for the treatment of adults with
• Newly diagnosed Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML)…

Tasigna (Nilotinib)

Overview
Tasigna is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat adults with Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) — a type of myeloproliferative…

Vonjo (Pacritinib)

Overview
Vonjo is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with certain types of myelofibrosis. Vonjo is also known by its generic name, pacritinib
Vonjo is part…

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