Hi Jen,
The biopsies and aspiration revealed a new issue (abnormal karyotype) BUT it also showed that my blast counts are still at 1% which is great news. No reversal of fibrosis but it seems to be “stable” for now except for the abnormal karyotype. Bothoncologists/hematologists that I see agree that it confirms that treatment (clinical trial) is causing the disease to stabilize; but both are concerned about the abnormality since it is new. The previous 2 bone marrow biopsies/aspirations showed a normal karyotype which have been within 10 months. It’s a watch and wait game to see what that means down the road. My next biopsy is in April. They are NO fun but give the most information! Prayingthrough✝️🙏🏼
I hope this was helpful.😊

I was 54 when diagnosed which I think is on the lower end. I believe the average age is around 65.

I was diagnosed at age 77 and now 78. Doing ok. I have some ups and downs. But living my life with PMF. You can do it!
Hugs
Judy

Sorry about the abnormal karyotype, but glad about the stabilizing with clinical trial.

Thank you Martin for your response. When I was diagnosed, I already had disease burden such as severe fatigue, anemia, enlarged spleen, itching, bone pain, etc…. But I am in a clinical trial and it has helped. I too am nervous about my appointments this week with the doctor, clinical team, and the bone marrow biopsy with aspiration. This appointment will show if my Myelofibrosis has progressed or stood still. Many prayers to you!!