Yes I have it now for 3rd or could be 4 th I’m beginning to think it is something to do with having MPN .

I wonder if it has to do with my immune system

Shingles is in the herpes virus group. I’ve never had shingles, but I have to take Valtrex every single day because I get cold sores on my mouth constantly, which is in the herpes virus group too. I wonder would it be effective for your condition? Ask your care team and see what they say. I would be interested because just like you, even being on medication, I am still getting breakthroughs on the fever blisters.

Hi Julie,

This study might be of interest to you:
"These novel findings of an overall increased risk of infections in MPN patients, irrespective of common cytoreductive treatments, suggest the increased risk of infection is inherent to the MPN."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC77...

Many hugs of support,
Tatiana

I am taking Jakafi. Shingles apparently a side effect of the medication. I developed Postherpatix Neyralgy from my Shingles.
I had both Shingrix vaccines 3 years prior dye to ET DX
I started taking antiviral on day 2 and continued 30 days. I started seeing an Accupuncturist for the first time ever. I am still seeing Accupuncturist but am feeling so much better! What a journey. Trying to figure out how to boost immunity as I currently have zilch. So sorry to hear of others with this.