Anagrelide stopped reducing my platelets so when I had the bone marrow biopsy, they put me on Jakafi. There are a couple of new drugs that may even be more suitable. You might want to try to see an MPN specialist in Fla. the more knowledge you get, the better your treatment will be. Good luck

Hi Kathryn: I have been on Anagrelide and Hydroxyurea since I got diagnosed with ET back in 2005 (or so). They kept me on them when it progressed to Myelofibrosis. They wanted to do a bone marrow transplant back in 2020 but I declined at that time (Covid had just started). I do not see an MPN specialist here in Florida, just my oncologist/hematologist but I do see one when I visit my boys in MA. I’ve asked if I should try something else bcuz I get heart palpitations, extreme (at least to me) tiredness and just can’t seem to get myself going sometimes. I get really bloated and gassy no matter what I eat. I just hate feeling blah so much, I force myself to get up and go to get blood work and I try to make lunch dates with friends just so I don’t sit around. Now I’ve got this dryness and bump on my finger that just won’t go away. Am taking antibiotics for it and if they don’t work will have to see hand specialist

If you look at my story, i had a similar situation. What medication are you taking for MF? When i went on Jakafi , my platelets reduced to normal. Being anemic is partly why I’m so tired but MF also makes you tired. I also get full very easy but my spleen is not enlarged. You may want to check with your dr. Is he/she an MPN specialist?