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Exhaustion is a symptom of MPNs, and so is body pain. While stress might accentuate them, when one has an MPN, it is far more likely they are there due to the MPN. There are some good articles on this website on how to handle fatigue, especially related to energy saving. There are actually pacing programs on physiotherapy websites that can help with energy saving.

Below there is some research on MPN symptoms:
"Prominent symptoms include fatigue (92.7%), early satiety (61.9%), abdominal pain (45.9%), abdominal discomfort (53.2%), inactivity (60.5%), headache (48.3%), concentration problems (61.7%), dizziness (55.2%), numbness (61.3%), insomnia (65.4%), sad mood (62.7%), sexuality problems (57.9%), cough (46.4%), night sweats (56.4%), itching (52.6%), bone pain (48.5%), fever (20.2%), weight loss (34.2%), and impaired quality of life (84.2%)"
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC46...

"Fatigue in MPN is common, debilitating and distressing. It affects all aspects of health, wellbeing and life. Health professionals could affect patients' lives substantially by acknowledging and understanding fatigue in MPN, including contributing factors and potential opportunities for management. More systematic data describing the causes and management of MPN fatigue is needed."
https://onlinelibrary.wiley.com/doi/epdf/10.100...

Regarding pain, this article is a good read:
https://www.mympnteam.com/resources/pain-and-mp...

"Chronic pain (abdominal, bone) is a prevalent and undermanaged feature of MPN disorders. Chronic non-MPN pain is further complicated by the development of the disorder. Many MPN patients lack understanding on its prevalence and furthermore feel ill-equipped to manage it. Patients have, however, found symptomatic benefit from various pharmacological and non-pharmacological treatment modalities that require further exploration. Results from this study suggest MPN patients should be assessed regularly for pain and offered early referral to specialized services for evaluation, source identification and treatment."
https://ashpublications.org/blood/article/132/S...

I hope you get all the support that you need to reduce your symptoms.

Pain and MPNs: Causes and Management | myMPNteam

https://www.mympnteam.com/resources/pain-and-mpns-causes-and-management

Impact of Inflammation on Myeloproliferative Neoplasm Symptom Development

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619953/

Hello Renee
I'm glad you're here.
Fatigue is a very common side effect of MPNs. I often wonder if my fatigue is just caused by my age (73) or my MPN (ET). But I think it's more likely the ET. It's not like usual tiredness. Sometimes I just CAN'T, and that's never been a problem before.
You might want to take a look at the link below, which is one of the many resources on this site.
Good luck!
https://www.mympnteam.com/resources/managing-fa...

Managing Fatigue With MPNs | myMPNteam

https://www.mympnteam.com/resources/managing-fatigue-with-mpns

Stress can really take a toll on your body, and it is so difficult to pinpoint causes, in my 23 years experience.

I had a shower of pulmonary embolisms before my diagnosis in 2001, presenting only as slight shortness of breath, also a small brain stem hemorrhage, which presented as a vision change and loss of balance.

I would ask your Doctor what you should be concerned about…take in written questions and write down the answers…and, of course, listen to your instincts and call your Dr. or get into a prompt care if you are concerned.

All the best, and please keep us posted here.

Energetic, intelligent, high-functioning people may tend to overthink and worry too much. I'm no expert, but my reading suggests there may be overproduction of the stress hormones cortisol and adrenaline. For decades I've taken a very low dose (10 mg) of Lexapro (generic: Escitalopram) for stress. This started when I was having serious family issues, but has been helpful ever since. I feel no need to increase it. ET entered my life four years ago. When I changed to a new blood specialist last December, I specifically asked him if taking 10 milligrams of Lexapro was OK. He said that was fine, and added: "Maybe we all should be doing that."

Hola René, efectivamente la fatiga es un síntoma típico de las MPN, pero no es menos cierto que el estrés contribuye a aumentar esa fatiga, y no debemos olvidar que estamos en primavera y llega con astenia primaveral. En mi caso nunca había sentido astenia primaveral hasta que me diagnosticaron ET, por lo que deduzco que las MPNs amplifican los efectos de la misma. Espero que con el final de curso pueda volver a estar relajada y vuelva su energía. Saludos