Common symptoms of Polycythemia Vera (PV) include:
• Weakness and fatigue that doesn't improve with rest
• Headaches and dizziness
• Itchy skin, especially after warm showers
• Facial redness and flushing
• Night sweats
• Enlarged spleen (occurs in 75% of cases)
• Bone and joint pain
• Vision problems
• Blood clots
• High Show Full Answer
Common symptoms of Polycythemia Vera (PV) include:
• Weakness and fatigue that doesn't improve with rest
• Headaches and dizziness
• Itchy skin, especially after warm showers
• Facial redness and flushing
• Night sweats
• Enlarged spleen (occurs in 75% of cases)
• Bone and joint pain
• Vision problems
• Blood clots
• High blood pressure
Some people may experience these symptoms for years before getting diagnosed since PV is rare and symptoms can be vague. Treatment options for PV typically include:
• Regular phlebotomy (blood removal)
• Daily aspirin to prevent blood clots
• Hydroxyurea medication
• Interferon alfa (mainly for pregnant women or those who may become pregnant)
• Jakafi (ruxolitinib) for those who don't respond to hydroxyurea
• Clinical trials testing new treatments
With appropriate treatment, people with PV typically have a median survival of 10-20 years. The key focus of treatment is preventing complications like thrombosis and bleeding.
September 17, 2025