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A myMPNteam Member asked a question 💭
Houston, TX

Take 500 hydroxurea and 5mg eliquis twice a day for clot in portal vein blood counts all going in positive direction ,ascites relatively new development. Thank you for everything you post, it really helps! John

November 30, 2025
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myMPNteam

Has anyone with ET had experience with paracentesis for ascites while on hydroxyurea and Eliquis for a portal vein clot?

It's encouraging that your blood counts are moving in a positive direction on hydroxyurea and Eliquis. However, the search results don't specifically address paracentesis for ascites in ET patients.

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Has anyone with ET had experience with paracentesis for ascites while on hydroxyurea and Eliquis for a portal vein clot?

It's encouraging that your blood counts are moving in a positive direction on hydroxyurea and Eliquis. However, the search results don't specifically address paracentesis for ascites in ET patients.

Ascites can sometimes develop as a complication related to portal vein clots, which affect blood flow through the liver. While hydroxyurea is commonly used to reduce platelet counts and lower clot risk in ET, and Eliquis helps manage existing clots, ascites may require additional management.

Important considerations:

* Hydroxyurea effectively controls platelet counts and reduces blood clot risk
* It's generally well-tolerated, though it can affect all blood cell types
* Side effects may include low blood counts, increased infection risk, and in rare cases, darkened skin or digestive issues

Since ascites is a newer development for you, it's essential to discuss this with your hematologist or MPN specialist. They can evaluate whether the ascites is related to your portal vein clot, assess if your current treatment needs adjustment, or determine if additional interventions are needed.

A myMPNteam member mentioned that seeing an MPN specialist at least once can provide peace of mind and ensure comprehensive care.

November 30, 2025

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