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Real members of myMPNteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
March 15
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Does essential thrombocythemia make it harder to fight colds and infections?

Yes, ET can make it harder for your body to fight off infections like colds. People with myeloproliferative neoplasms, including ET, have a significantly higher risk of developing bacterial, viral, and fungal infections compared to others their Show Full Answer

Does essential thrombocythemia make it harder to fight colds and infections?

Yes, ET can make it harder for your body to fight off infections like colds. People with myeloproliferative neoplasms, including ET, have a significantly higher risk of developing bacterial, viral, and fungal infections compared to others their age without MPNs.

Your experience of a cold lasting three weeks and developing into a sinus infection requiring antibiotics is consistent with what can happen with ET. Research shows that people with MPNs face increased risks of:

- Pneumonia
- Urinary tract infections
- Viral hepatitis
- Sepsis (a dangerous reaction to infection)

The increased infection risk comes from two main sources:

1. The MPN itself affects your immune system's ability to fight infections
2. Treatments used to manage MPNs, particularly JAK2 inhibitors, can reduce the activity of certain immune cells, lowering your body's defenses

Because infections are more likely to become serious when you have ET, it's important to monitor symptoms closely and seek medical attention when infections don't resolve as quickly as they normally would.

March 15

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