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Real members of myMPNteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A myMPNteam Member asked a question 💭
Woodstock, GA
April 12
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A myMPNteam Member

Yes, it's okay. But, if you have conditions that put you at risk for stroke or heart attack, maybe not. The NCCN guidelines indicate no treatment (cytoreduction) is necessary until platelets are at 1 m or higher. This is if you are under 60 years old and no other risky health issues. There have been studies that have indicated there is no correlation between platelet count and stroke or heart attack.

May I ask....why are you asking? Are you not feeling well with your platelets in the 700,000's? How are you doing?

April 13
myMPNteam

Is a platelet count of 700,000 per microliter concerning?

A platelet count of 700,000 is elevated, as normal levels range from 150,000 to 400,000 per microliter. However, having high platelet counts doesn't automatically mean you need treatment or are at immediate risk.

Your doctor focuses less on the number itself and Show Full Answer

Is a platelet count of 700,000 per microliter concerning?

A platelet count of 700,000 is elevated, as normal levels range from 150,000 to 400,000 per microliter. However, having high platelet counts doesn't automatically mean you need treatment or are at immediate risk.

Your doctor focuses less on the number itself and more on what it means for your symptoms and potential complications. Many people with MPNs live normally with elevated platelet counts without requiring treatment.

What matters more than the number:

- Your age and medical history
- Whether you've had blood clots before
- Your specific gene mutation (JAK2, CALR, or MPL)
- Any symptoms you're experiencing

Interestingly, research shows that high platelet counts aren't strongly linked to blood clot risk. In fact, extremely high counts (over 1 million to 1.5 million) are more associated with bleeding problems than clotting.

If you're at low risk for complications, your doctor may recommend a "watch and wait" approach. People at higher risk may need medications to help manage platelet levels.

Talk with your doctor about your specific situation and whether your platelet count requires any action.

April 12

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