I asked my hematologist this question and basically in terms of blood loss. . .no. You may feel better as your blood isn’t so thick. I know I do. I can’t wait for my next one on the 13th.
As the AI responded, repeated phlebotomies have their own issues in terms of iron depletion. But as long as your hematocrit is above normal, you’re not at risk of blood depletion. We have lots of extra to spare 🙂 But some may have reactions to that much blood being removed at once and need smaller amounts removed to prevent those issues from occurring.
May 7 (edited)
Is too much blood being taken during phlebotomy a concern with polycythemia vera (PV)?
Phlebotomy is the standard treatment for PV, and typically up to one pint (500 milliliters) of blood is drawn per session — similar to donating blood. The goal is to bring hematocrit levels below 45 percent. One real risk with repeated Show Full Answer
Is too much blood being taken during phlebotomy a concern with polycythemia vera (PV)?
Phlebotomy is the standard treatment for PV, and typically up to one pint (500 milliliters) of blood is drawn per session — similar to donating blood. The goal is to bring hematocrit levels below 45 percent. One real risk with repeated phlebotomy sessions is iron deficiency. Here's how that cycle can unfold:
- Repeated phlebotomies gradually deplete iron levels
- Low iron causes its own uncomfortable symptoms
- If iron is supplemented to fix the deficiency, it can fuel more red blood cell production
- That then leads to needing even more phlebotomies
It's worth raising any concerns about how much blood is being drawn, or symptoms felt afterward, directly with a hematologist. Some lightheadedness or dizziness after a session is not unusual. A few helpful tips to manage this:
- Drink about 8 glasses of water the day before the procedure
- Continue staying well hydrated for a day or two after
- Avoid alcohol, caffeine, and tobacco for the rest of the day after the procedure
- Skip strenuous exercise for at least one day afterward
May 6