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Real members of myMPNteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A myMPNteam Member asked a question 💭
Mountain Top, PA
May 7
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A myMPNteam Member

Hi LeeAnn, MT. Top, I am originally from Hazleton!! When I grew up there, it was a small town with wonderful people. I don’t even recognize it today, very sad. I was diagnosed with ET, CALR and TP 53 mutations in 2017. I have been taking hydroxyurea and low dose aspirin since then. I have not experienced any bone or muscle pain. I hope you feel better. Michele😊

May 8
A myMPNteam Member

Thank you Michelle!

May 8
myMPNteam

Yes, bone and joint pain can be symptoms of MPNs, including ET. These types of pain are fairly common and can stem from a few different causes:

- Bone pain may result from overproduction of blood cells in the bone marrow, causing crowding and inflammation in the surrounding tissue
- Joint pain can occur due to a buildup of Show Full Answer

Yes, bone and joint pain can be symptoms of MPNs, including ET. These types of pain are fairly common and can stem from a few different causes:

- Bone pain may result from overproduction of blood cells in the bone marrow, causing crowding and inflammation in the surrounding tissue
- Joint pain can occur due to a buildup of uric acid, which can lead to painful swelling in the joints
- Thicker, stickier blood (known as hyperviscosity) associated with ET can also contribute to discomfort Hydroxyurea itself can also be a contributing factor. Known side effects of hydroxyurea include body aches and joint pain, so it's possible the medication is playing a role in what's being experienced.

It's really worth bringing this up with a doctor, as they can help figure out whether the pain is coming from ET itself, the treatment, or a combination of both. Never stop or adjust medication without speaking to a doctor first.

May 7

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