... When these proteins are blocked, the CML cells die.Several TKIs are used to treat MPNs: Asciminib (Scemblix) and ponatinib (Iclusig) — These are prescribed to treat CML that does not respond to other TKIs. Bosutinib (Bosulif) — This drug is used to treat Philadelphia chromosome-positive CML in the chronic phase. ...
7 Treatment Options for Myeloproliferative Neoplasms
... When these proteins are blocked, the CML cells die.Several TKIs are used to treat MPNs: Asciminib (Scemblix) and ponatinib (Iclusig) — These are prescribed to treat CML that does not respond to other TKIs. Bosutinib (Bosulif) — This drug is used to treat Philadelphia chromosome-positive CML in the chronic phase. ...