The use of Interferon should be started immediately and pray for the cure within a couple of years.

The magic age to begin taking meds depends on your counts, you symptom burden, and how much those counts and burdens are negatively impacting your health and quality of life.

MPNs are slow growing blood cancers. Normally they are rather advanced by the time symptoms become the catalyst for seeking medical care.

Hope this helps

I'll be turning 72 in a few weeks. I just started taking one baby aspirin per day for PV. My doc seems happy to go slow on medicines at this point, none of my blood counts has hit one million yet, no blood letting yet. I also see her for MGUS.

Stephen, I have been on Hydrea, anagrelide, Jakafi while on anagrelide, pegasys, and I’m now on a clinical trial medication, bomedemstat. My platelets run between 700,000 and 925,000 on the medicine. It is my understanding that about 85% of patients on bomedemstat in order to reduce their platelet counts, do so within an initial 24-28 week trial period and continue on the medication. I have been on the medication for almost three years. Given it keeps my platelets from sky rocketing and absolute reduction may be greater than someone who starts with platelets at, say, 650,000, I have a potential greater reduction. I do have nausea that is treated but it has recently started to lessen. My body tolerates the bomedemstat more than the other medications.

I don't think immunosuppressed folks with transplants (like me) can take interferon meds, at least, not besremi.