I have been an RN for the last 30 years, assisted with bedside BMB for various medical issues. (None were for MPN). I never heard of MPN’s until recently. Anyway, i asked a lot of questions and my Dr said 1) it will give a definitive diagnosis, 2) they can check for scarring of the bone marrow.. so now I know for a fact I have ET / CALR and no scarring.

BMB is still the best way to diagnose. I was originally diagnosed with a form of Leukemia and it was only the biopsy that definitively showed PMF. Of course that changed the plan!

BMB clarified diagnosis of ET JAK2. I don't think that it altered treatment particularly. Recommended treatment was HU according to the algorithm for over 60, JAK2. Not a lot of thought put into it. BMB, diagnosis, algorithm medication recommendation.

I still have not been offered any BMB, 2 MPN specialist, 4 yrs now baby asprin and 500 hu 3 days a week only. HU was bothering my stomach at 500 per day.... so cut back last yr. Platelets under 700, age 72.