myMPNteam

Why are you still experiencing tiredness and nausea despite your current treatment?

Fatigue and nausea can persist even when your platelet count is well-controlled. These symptoms may be related to your MPN itself, side effects from your medications, or a combination of both.

Hydrea (hydroxyurea) is known to cause nausea Show Full Answer

Why are you still experiencing tiredness and nausea despite your current treatment?

Fatigue and nausea can persist even when your platelet count is well-controlled. These symptoms may be related to your MPN itself, side effects from your medications, or a combination of both.

Hydrea (hydroxyurea) is known to cause nausea as a side effect. Some myMPNteam members have found relief by taking it before bed or with food, as taking it on an empty stomach can worsen nausea.

Fatigue is one of the most common symptoms in MPNs and can occur regardless of blood counts. It may be caused by:
* The MPN itself
* Medication side effects (both Hydrea and aspirin can contribute)
* Other factors like depression, anxiety, or other medications you might be taking

Your platelet count of 385 is actually within a reasonable range, so the tiredness isn't necessarily related to high platelets. It's important to talk with your doctor about these symptoms. They may be able to:
* Adjust your medication timing or dosage
* Evaluate whether other medications you're taking could be contributing to fatigue
* Check for other factors like anemia or thyroid issues
* Consider whether treatment for depression or anxiety might help

Some members have found that taking Hydrea before bed helps reduce nausea. However, don't change your medication schedule without consulting your healthcare team first.

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

Managing Fatigue With MPNs

Side Effects of Common MPN Treatments