Progressing dizziness and ringing in the ears (tinnitus) are recognized symptoms of ET, often linked to how platelets interact with small blood vessels. These are sometimes called "microvascular symptoms." With a CALR mutation, it's really important to keep your care team updated when symptoms are getting worse. As for Show Full Answer
Progressing dizziness and ringing in the ears (tinnitus) are recognized symptoms of ET, often linked to how platelets interact with small blood vessels. These are sometimes called "microvascular symptoms." With a CALR mutation, it's really important to keep your care team updated when symptoms are getting worse. As for exercise lowering platelet counts — exercise alone is not a recognized medical treatment for reducing platelet counts in ET. The MPN Research Foundation does recommend regular exercise as a helpful way to manage energy levels and overall wellbeing, but it won't meaningfully move the needle on platelet numbers.
Treatments that actually help lower platelet counts include:
- Baby aspirin — often used for low-risk patients to reduce platelet "stickiness" and relieve microvascular symptoms like dizziness and ringing in the ears
- Cytoreductive medications — such as hydroxyurea, interferon, or anagrelide, typically used for higher-risk patients
- Plateletpheresis — a procedure that physically removes platelets from the blood, used in more urgent situations
The good news is that your symptoms (dizziness, ringing in ears) are exactly the kind that aspirin or cytoreductive therapy can help relieve. Definitely bring up the progression of these symptoms with your hematologist — there may be a good reason to revisit or adjust your current treatment plan.
May 18
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